Multiple answers.
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I have already built 384x256 with 3 chains, are you ok going from 320 to 384 instead? If so, check Marc's Blog: arduino - RGB Panels, from 192x80, to 384x192, to 384x256 and maybe not much beyond
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Interesting 6 port board: Beaglebone Pocketcroller V2 - #2 by marcmerlin supports 6 chains, but I have not heard back from anyone working on this what lib it is and whether it’s close enough to rpi-rgb-panels
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I’ve heard that electrodragon (who makes the current active-3 board) is potentially working on a 6 channel board for CM4 using this lib. It doesn’t exist yet, but it may soon. I think you can get a carrier board for cheap: Amazon.com: Compute Module 4 to Raspberry Pi 4 Adapter, Connect CM4 to Replace Raspberry Pi 4B, Alternative for Pi 4,Onboard 4-ch USB 3.0,RJ45 Gigabit Ethernet Port,PoE Header,Compatible with Pi 4B Series Hats : Electronics
@hechaogm , do you know what carrier board can be used for the CM4 without creating I/O conflicts if one would want 4 to 6 channels? Would the CM4 HUB75 adapter board be a carrier board and offer basic I/O to it?